6 research outputs found
Supplementary Figure S3 from Progressive Spreading of DNA Methylation in the <i>GSTP1</i> Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer
Supplementary Figure S3 shows the GSTP1 promoter methylation and its corresponding GSTP1 immunohistochemistry expression for PIA and PIN lesions within an individual patient, and notably the heterogeneity of the PIA lesions.</p
Supplementary Figure S1 from Progressive Spreading of DNA Methylation in the <i>GSTP1</i> Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer
Supplementary Figure S1 shows the phased methylation by allele of the GSTP1 promoter region classified by density of methylation.</p
Supplementary Table S3 from Progressive Spreading of DNA Methylation in the <i>GSTP1</i> Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer
Supplementary Table S3 shows the phased methylation of the GSTP1 promoter region across 908 alleles, or clones, classified by density of methylation.</p
Supplementary Table S1 from Progressive Spreading of DNA Methylation in the <i>GSTP1</i> Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer
Supplementary Table S1 shows patient and tumor characteristics from the patients who underwent radical prostatectomies for this study.</p
Supplementary Table S2 from Progressive Spreading of DNA Methylation in the <i>GSTP1</i> Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer
Supplementary Table S2 shows the phased methylation of the GSTP1 promoter region across 102 lesions classified by density of methylation.</p
Supplementary Figure S2 from Progressive Spreading of DNA Methylation in the <i>GSTP1</i> Promoter CpG Island across Transitions from Precursors to Invasive Prostate Cancer
Supplementary Figure S2 shows the methylation rate by allele of the GSTP1 promoter region for partially methylated PIN alleles and demonstrates a hotspot of methylation around transcription factor binding sites and the transcription start site.</p